刘芬,女,1990年出生,湖南衡阳人,博士(博士后)。主要从事中药及天然药物活性成分研究,同时也涉及新型功能天然分子的快速发现、中药制剂和食品成分分析、以及药材质量标准建立等领域。目前在国内外学术刊物发表研究论文14篇,以第一作者发表SCI论文8篇;主持国家自然科学基金青年科学基金项目1项,参与国家自然科学项目4项。联系方式:liufen0224@126.com。
研究方向:
中药及天然药物活性成分研究;新型功能天然分子的发现与研究
工作经历:
2024.2−至今 伟德国际BETVlCTOR1946,伟德BETVLCTOR1946
2020.01−2023.12 暨南大学,生物活性分子与成药性优化全国重点实验室,博士后
教育经历:
2015.09−2019.12 暨南大学,中药化学,医学博士
2012.09−2015.06 暨南大学,有机化学,理学硕士
2008.09−2012.06 伟德国际BETVlCTOR1946,应用化学,工学学士
科研项目:
国家自然科学基金青年科学基金项目,82003613,金蒲桃中新型间苯三酚类成分抗RSV的构效关系和作用机制研究,2021/01-2022/12,16万元,主持.
国家自然科学基金青年科学基金项目,41506156,侧扁软柳珊瑚三株共生菌中抗海洋污损活性代谢产物,2016/01-2018/12,20万元,参与.
国家自然科学基金面上项目,41376155,珊瑚中抗污损活性物质研究,2014/01-2017/12,82万,参与.
国家自然科学基金面上项目,21372100,Phakellia属海绵中抗肿瘤活性环肽化合物的发现,2014/01-2015/12,40万,参与.
学术论文:
Zhang Jin-Yan#, Liu Fen#, Jin Qian, Li Xue-Yi, Zhan Qiong, Chen Mu, Wang Si-Si, Wu Zhen-Long*, Ye Wen-Cai*, Wang Lei*. Discovery of unusual phloroglucinol–triterpenoid adducts from Leptospermum scoparium and Xanthostemon chrysanthus by building blocks-based molecular networking. Chinese Chemical Letters, 2023: 108881. (共同第一作者,JCR 1区,IF=9.1)
Liu Fen#, Tian Hai-Yan#, Huang Xiao-Lin, Wang Wen-Jing, Li Ni-Ping, He Jun, Ye Wen-Cai*, Wang Lei*. Xanthchrysones A-C: rearranged phenylpropanoyl-phloroglucinol dimers with unusual skeletons from Xanthostemon chrysanthus. Journal of Organic Chemistry, 2019, 84(23): 15355-15361. (JCR 2区,IF=4.2,TOP期刊)
Liu Fen#, Wu Yan#, Li Ni-Ping, Liu Jiao-Wen, Wang Lei*, Ye Wen-Cai*. Chiral isolation and absolute configuration of (+)- and (-)-xanchryones F and G from Xanthostemon chrysanthus. Chemistry & Biodiversity, 2020, 17(1): e1900683. (JCR 3区,IF=2.9,封面文章)
Liu Fen#, Chen Mei-Hong#, Hu Yan-Xia, Zhan Qiong, Zhang Jin-Yan, ZhangZi-Yue, Wang Si-Si, Ye Wen-Cai*, Wang Lei*. Xanchryones I-N, six unusual phloroglucinol-amino acid hybrids from the leaves of Xanthostemon chrysanthus. Chemistry & Biodiversity, 2023, 20(4): e202300234. (JCR 3区,IF=2.9)
Liu Fen, Lu Wei-Jin, Li Ni-Ping, Liu Jiao-Wen, He Jun, Ye Wen-Cai*, Wang Lei*. Four new cinnamoyl-phloroglucinols from the leaves of Xanthostemon chrysanthus. Fitoterapia, 2018, 128: 93-96. (JCR 3区,IF=3.4)
Sun Huan#, Liu Fen#, Feng Mei-Ran, Peng Qi, Liao Xiao-Jian, Liu Ting-Ting, Zhang Jun*, Xu Shi-Hai*. Isolation of a new cytotoxic polyhydroxysterol from the South China Sea soft coral Sinularia sp.. Natural Product Research, 2016, 30(24): 2819-2824. (共同第一作者,JCR 3区,IF=2.2)
Peng Qi#, Liu Fen#, Sun Huan, Liao Xiao-Jian, Feng Mei-Ran, Liu Ting-Ting, Xu Zheng-Xiong, Zhang Jun*, Xu Shi-Hai*. A new sesquiterpene from the gorgonian coral Menella sp.. Natural Product Research, 2016, 30(20): 2299-2304. (共同第一作者,JCR 3区,IF=2.2)
Liu Fen, Li Shuo, Ju Zhi-Ran, Liu Ting-Ting, Liang Rui-Yu, Liao Xiao-Jian, Xu Shi-Hai*. N-(3-aminopropyl)subergorgamide, a new alkaloid from the gorgonian Paraplexaura sp.. Journal of Asian Natural Products Research, 2015, 17(8): 851-855. (JCR 4区,IF=1.7)